Dr LEUNG Lai Han, Elaine | eleung@pathology.hku.hk

Oversea Research Training

Reproductive Biology Unit and Division of Gynecologic Oncology, Department of Obstetrics & Gynecology and Cellular & Molecular Medicine, University of Ottawa, Hormones, Growth and Development Program, Ottawa Health Research Institute, The Ottawa Hospital (Civic Campus) (2005)

Awards and Honors

1. University of Hong Kong/China Medical Board Grants 2007/2008 - Support training and conducting lung cancer stem cells research at the Department of Pathology, Nevada Cancer Institute (NVCI), Las Vegas, USA
   

Recent Publication Lists

Leung EL, Fiscus RR, Tung JW, Tin VP, Cheng LC, Sihoe AD, Fink LM, Ma Y and Wong MP. Non-Small Cell Lung Cancer Cells Expressing CD44 Are Enriched for Stem Cell-Like Properties. (2010) (Accepted by PLoS ONE) (In press)

Wong DW, Leung EL, Wong SK, Tin VP, Sihoe AD, Cheng LC, Au JC, Chung LP, Wong MP. A Novel KIF5B-ALK Variant in Non-Small Cell Lung Cancer. (2010) (Accepted by Cancer) (In press)

Leung EL, Wong JC, Johlfs MG, Tsang BK, Fiscus RR. Protein kinase G type Ia activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation. Molecular Cancer Research. 2010 Apr;8(4):578-91.

Gai H, Leung EL, Costantino PD, Aguila JR, Nguyen DM, Fink LM, Ward DC, Ma Y. Generation and Characterization of Functional Cardiomyocytes using Induced Pluripotent Stem Cells derived from Human Fibroblasts. Cell Biol Int. 2009 Nov;33(11):1184-93.

Tam IY1*, Leung EL*, Tin VP, Chua DT, Sihoe AD, Cheng LC, Chung LP and Wong MP. Double EGFR mutants containing rare EGFR mutant types show reduced in vitro response to gefitinib compared to common activating missense mutations. Molecular Cancer Therapeutics. 2009 Aug 11* Both authors contributed equally to this work.

Leung EL, Tam IY, Tin VP, Chua DT, Sihoe AD, Cheng LC, Ho JC, Chung LP and Wong MP. Src promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy. Molecular Cancer Research. 2009 Jun;7(6):923-32

Wong DW, Leung EL, So KK, Tam IY, Sihoe AD, Cheng L, Tin VP, Ho KK, Ho JC, Chua DT, Au JS, Chung LP, Wong MP. The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS. Cancer. 2009 April 15; 115(8):1723-33

Leung EL, Fraser M, Fiscus RR and Tsang BK. Cisplatin alters nitric oxide synthase levels in human ovarian cancer cells: involvement of p53 regulation and cisplatin resistance. Br J Cancer. 2008 Jun 3;98(11):1803-9