Professor CHAN Li Chong
Chair Professor
MA Cantab;
PhD Lond;
FRCP Lond;
FRCPath;
FHKAM (Pathology);
FHKAM (Medicine)
What causes leukaemia? How to make better and caring doctors?
Education
- Program Director of the Research and Scholarship in Medical and Health Sciences Education (IMHSE), LKS Faculty of Medicine
- Co-Ordinator, Task Force in Medical Humanities, LKS Faculty of Medicine
- Co-Director, The Centre for the Humanities and Medicine, the University of Hong Kong
- Leader, Working Group on the AoI in Scientific & Technological Literacy, Common Core Curriculum Committee
- Member, Common Core Curriculum Steering Committee
- Chairman, Organising Committee of “Making Doctors Human” Frontiers in Medical Education, HKU Dec 2008
Research Interest
- Aetiology, cellular and molecular biology of leukaemias
Teaching Philosophy
My teaching philosophy is driven by the recognition that “The student of today is the teacher of tomorrow”. Implicit in this statement is our responsibility to nurture students to develop not only self directed learning and critical thinking skills but also a spirit of inquisitiveness and the courage to challenge scientific and medical dogma.
I am delighted that the Li Ka Shing Faculty of Medicine will be introducing medical humanities as part of the core curriculum for medical students from 2012. The practice of medicine, a science as well as an art, will also require students to understand the limits of medicine, the nature of human suffering and the dangers of the medicalisation of life in terms of its social, ethical and economic impact.
Through the teaching and learning of medical humanities, students can generate new inquiries and reflections which will enable them to understand illness and health in the wider context of the lives of people. They should become aware of the complexities and ambiguities of issues involved in medical care and practice; and explore the nature of suffering & healing so as to enable patients to live a life of meaning despite their illness.
Awards and Honors
- The University of Hong Kong Outstanding Teacher Award 2008
- Faculty Teaching Medal 2006
- Universities 21 Teaching Fellowship 2007
- Outstanding Teaching Award 2009, The University of Hong Kong
- Ron Harden Innovation in Medical Education Award, 7th International Medical Conference, International Medical University, Kuala Lumpur in March 2010 (based on a medical humanities special study module developed by Julie Chen, LC Chan and DJ Salter)
Selected Publications
Click here for detail publication list on PubMed
Research
Sun Q, So CC, Yip SF, Wan TSK, Ma SK, Chan LC. Functional alterations of Lin- CD34+ CD38+ cells in chronic myelomonocytic leukemia and on progression to acute leukemia. Leukemia Research 2008.
Sun Q, Kong CT, Huang FP, Chan LC. Aberrant dendritic cell differentiation initiated by the Mll-Een fusion gene does not require leukemic transformation. J Leukoc Biol 2008.
Kong CT, Sham MH, So CWE, Cheah KSE, Chen SJ, Chan LC. The Mll-Een knock-in fusion gene enhances proliferation of myeloid progenitors derived from mouse embryonic stem cells and causes myeloid leukemia in chimeric mice. Leukemia 2006.
Yam JWP, Jin D-Y, So CW, Chan LC. Identification and characterization of EBP, a novel EEN binding protein that inhibits ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein. Blood 2004.
Chan LC, Tam TH, Li CK, Lau YL, Li CK, Yuen HL, Lee CW, Ha SY, Yuen P, Leung NK, Patheal SL, Greaves MF, Alexander FE. Is the timing of exposure to infection a major determinant of childhood B precursor common acute lymphoblastic leukemia in Hong Kong. Paediatric & Perinatal Epidemiology 2002.
So CW, Dong S, So CKC, Cheng GX, Huang QH, Chen SJ and Chan LC. The impact of differential binding of wild-type RARa, PML-, PLZF- and NPM-RARa fusion proteins towards transcriptional co-activator, RIP-140, on retinoic acid responses in acute promyelocytic leukemia, Leukemia 2000.
So CW, Caldas C, Liu MM, Chen SJ, Huang QH, Gu LJ, Sham MH, Wiedemann LM and Chan LC. EEN encodes for a member of a new family of SH3-containing proteins and is the third gene located on chromosome 19p13 which fuses to MLL in human leukaemia, Proceedings of the National Academy of Sciences 1997.
Chan LC, Karhi KK, Rayter SI, Heisterkamp N, Eridani S, Powles R, Lawler SD, Groffen J, Foulkes JG, Greaves MF & Wiedemann LM. A novel abl protein is expressed in Philadelphia chromosome positive acute lymphoblastic leukaemia which does not involve the "breakpoint cluster region". Nature 1987.
Education
Chen JY, Salter DJ, Chan LC. Pen, brush and camera: outcomes-based medical humanities. Medical Education 2010.
Chan LC. Factors affecting the quality of problem-based learning in a hybrid medical curriculum. Kaohsiung Journal of Medical Sciences 2009.
Chan LC. The role of a PBL tutor: A personal perspective. 2007 International Problem-Based Learning Workshop, Kaohsiung Medical University, Taiwan. Kaohsiung Journal of Medical Sciences 2008.
Chan LC & Patil NG. Monograph 2: Problem-based learning (PBL): Everything you want to know and are not afraid to ask. IMHSE, Faculty of Medicine. 2006.
Chan LC, Nicholls J, Chan YS. Improving the quality of cases for problem-based learning (PBL): Experience and feedback from Year 1 medical students, University of Hong Kong. Journal Medical Education 2002.